{"id":935,"date":"2025-07-30T15:19:50","date_gmt":"2025-07-30T15:19:50","guid":{"rendered":"https:\/\/oralpathology.hiroshima-u.ac.jp\/?page_id=935"},"modified":"2025-08-02T14:40:15","modified_gmt":"2025-08-02T14:40:15","slug":"welcome","status":"publish","type":"page","link":"https:\/\/oralpathology.hiroshima-u.ac.jp\/index.php\/welcome\/","title":{"rendered":"Welcome page"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"935\" class=\"elementor elementor-935\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9767876 e-con-full e-flex e-con e-parent\" data-id=\"9767876\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b7aec57 elementor-widget elementor-widget-heading\" data-id=\"b7aec57\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/index.php\/welcome-to-oral-pathology-in-hiroshima-university\/\">Department of Oral and Maxillofacial Pathobiology, <br>\nHiroshima University<\/a><\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3b21be1 e-con-full e-flex e-con e-parent\" data-id=\"3b21be1\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cacf920 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"cacf920\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Japanese Page<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div 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href=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/index.php\/publications-en\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Publications<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cfe2e07 e-con-full e-flex e-con e-child\" data-id=\"cfe2e07\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4f376d3 elementor-widget__width-initial elementor-widget elementor-widget-button\" data-id=\"4f376d3\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/index.php\/presentations-en\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Presentations, Lectures, Awards, and Events<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-da22217 e-con-full e-flex e-con e-child\" data-id=\"da22217\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5014400 elementor-widget__width-initial elementor-widget elementor-widget-button\" data-id=\"5014400\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/index.php\/students-en\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">For Students and Residents<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ef6df64 e-flex e-con-boxed e-con e-parent\" data-id=\"ef6df64\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4c7f322 elementor-widget elementor-widget-html\" data-id=\"4c7f322\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div class=\"video-hero-wrapper\">\n  <video autoplay muted loop playsinline id=\"bg-video\">\n    <source src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/pixta_120697330_HD_1080.mp4\" type=\"video\/mp4\">\n    \u304a\u4f7f\u3044\u306e\u30d6\u30e9\u30a6\u30b6\u3067\u306f\u52d5\u753b\u304c\u518d\u751f\u3067\u304d\u307e\u305b\u3093\u3002\n  <\/video>\n\n  <!-- \u5de6\u4e0b\u306b\u8868\u793a\u3059\u308b\u30c6\u30ad\u30b9\u30c8 -->\n  <div class=\"video-text-overlay\">\n    <h1>Cancer Research<\/h1>\n\n  <\/div>\n<\/div>\n\n<style>\nbody, html {\n  margin: 0;\n  padding: 0;\n}\n\n.video-hero-wrapper {\n  position: relative;\n  width: 100vw;\n  height: 600px;\n  overflow: hidden;\n  z-index: 1;\n  margin-left: calc(-50vw + 50%);\n}\n\n#bg-video {\n  position: absolute;\n  top: 50%;\n  left: 50%;\n  min-width: 100%;\n  min-height: 100%;\n  transform: translate(-50%, -50%);\n  object-fit: cover;\n  z-index: -1;\n  background: black;\n}\n\n.video-text-overlay {\n  position: absolute;\n  bottom: 30px;\n  left: 30px;\n  color: white;\n  z-index: 2;\n  text-shadow: 0 0 10px rgba(0,0,0,0.7);\n}\n\n.video-text-overlay h2 {\n  font-size: 1.8rem;\n  margin: 0;\n}\n\n.video-text-overlay p {\n  font-size: 1rem;\n  margin: 10px 0 0 0;\n}\n<\/style>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a31033 elementor-widget elementor-widget-text-editor\" data-id=\"3a31033\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h1><b>\u3000Our Mission<\/b><\/h1><ol><li><h2><b>Advancing research into the mechanisms of oral and maxillofacial diseases, with a focus on oral cancer, and exploring new therapeutic strategies<\/b><\/h2><\/li><li><h2><b>Delivering high-quality diagnostic expertise in oral pathology through the work of experienced specialists<\/b><\/h2><\/li><li><h2><b>Cultivating future leaders in oral pathology who can excel on the international stage<\/b><\/h2><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e57a7b2 e-flex e-con-boxed e-con e-parent\" data-id=\"e57a7b2\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3f12777 e-con-full e-flex e-con e-child\" data-id=\"3f12777\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e5c7df4 elementor-arrows-position-inside elementor-pagination-position-outside elementor-widget elementor-widget-image-carousel\" data-id=\"e5c7df4\" data-element_type=\"widget\" data-settings=\"{&quot;slides_to_show&quot;:&quot;1&quot;,&quot;effect&quot;:&quot;fade&quot;,&quot;navigation&quot;:&quot;both&quot;,&quot;autoplay&quot;:&quot;yes&quot;,&quot;pause_on_hover&quot;:&quot;yes&quot;,&quot;pause_on_interaction&quot;:&quot;yes&quot;,&quot;autoplay_speed&quot;:5000,&quot;infinite&quot;:&quot;yes&quot;,&quot;speed&quot;:500}\" data-widget_type=\"image-carousel.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-carousel-wrapper swiper\" role=\"region\" aria-roledescription=\"carousel\" aria-label=\"\u753b\u50cf\u30ab\u30eb\u30fc\u30bb\u30eb\" dir=\"ltr\">\n\t\t\t<div class=\"elementor-image-carousel swiper-wrapper swiper-image-stretch\" aria-live=\"off\">\n\t\t\t\t\t\t\t\t<div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"1 of 6\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" 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class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/652034da3c6b0623f6136ad0-e1752393386406.jpg\" alt=\"652034da3c6b0623f6136ad0\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"5 of 6\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/65203a0f4e82aa24954d4158-e1752393423383.jpg\" alt=\"65203a0f4e82aa24954d4158\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"6 of 6\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/652034de4e82aa24954d40b8-e1752393516695.jpg\" alt=\"652034de4e82aa24954d40b8\" \/><\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-prev\" role=\"button\" tabindex=\"0\">\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-chevron-left\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M646 125C629 125 613 133 604 142L308 442C296 454 292 471 292 487 292 504 296 521 308 533L604 854C617 867 629 875 646 875 663 875 679 871 692 858 704 846 713 829 713 812 713 796 708 779 692 767L438 487 692 225C700 217 708 204 708 187 708 171 704 154 692 142 675 129 663 125 646 125Z\"><\/path><\/svg>\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-next\" role=\"button\" tabindex=\"0\">\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-chevron-right\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M696 533C708 521 713 504 713 487 713 471 708 454 696 446L400 146C388 133 375 125 354 125 338 125 325 129 313 142 300 154 292 171 292 187 292 204 296 221 308 233L563 492 304 771C292 783 288 800 288 817 288 833 296 850 308 863 321 871 338 875 354 875 371 875 388 867 400 854L696 533Z\"><\/path><\/svg>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"swiper-pagination\"><\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ff51ee4 e-con-full e-flex e-con e-child\" data-id=\"ff51ee4\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-48eef51 e-con-full e-flex e-con e-child\" data-id=\"48eef51\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36f7e07 elementor-widget elementor-widget-heading\" data-id=\"36f7e07\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Exploring the Pathogenesis of Oral Cancer<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f57d388 e-con-full e-flex e-con e-child\" data-id=\"f57d388\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e766401 elementor-widget elementor-widget-text-editor\" data-id=\"e766401\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"63\" data-end=\"498\">Cancer develops and progresses as a result of genetic alterations that abnormally regulate intracellular signaling pathways. We have revealed that aberrations in the Hippo pathway play a pivotal role in cell proliferation, drug resistance, and immune evasion in oral cancer. However, many aspects of this pathway and its pathological mechanisms remain elusive, and we continue to advance our research to achieve a deeper understanding.<\/p><p data-start=\"500\" data-end=\"791\">Our research extends beyond oral squamous cell carcinoma, which accounts for the majority of oral cancers, to include odontogenic tumors and salivary gland tumors. We aim to elucidate the mechanisms of tumor initiation and the factors driving disease progression in each of these conditions.<\/p><p data-start=\"793\" data-end=\"1207\">To this end, we employ a broad and cutting-edge range of approaches, including molecular biological analyses using human and mouse cancer cell lines, protein\u2013protein interaction studies, phosphoproteomics, multi-omics analyses of DNA, RNA, and proteins, bioinformatics, molecular pathology techniques, studies using genetically engineered mouse models and in vivo xenograft models, as well as single-cell analyses.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5ad3bce e-flex e-con-boxed e-con e-parent\" data-id=\"5ad3bce\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fd861f0 elementor-widget elementor-widget-heading\" data-id=\"fd861f0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Uncover the relationship between periodontal disease and systemic conditions<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-64bfd71 e-flex e-con-boxed e-con e-parent\" data-id=\"64bfd71\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8abc569 e-con-full e-flex e-con e-child\" data-id=\"8abc569\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-764390f elementor-widget elementor-widget-text-editor\" data-id=\"764390f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>We aim to elucidate the mechanisms linking periodontal disease to conditions such as non-alcoholic steatohepatitis, preterm birth, cardiovascular diseases, and Alzheimer&#8217;s-type dementia.<br data-start=\"193\" data-end=\"196\" \/>Our research involves analyses using oral bacteria and mouse models.<\/p><p data-start=\"92\" data-end=\"172\">We are promoting collaborative research between medical and dental sciences.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-813aa4d e-con-full e-flex e-con e-child\" data-id=\"813aa4d\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-52f185d elementor-widget elementor-widget-text-editor\" data-id=\"52f185d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Coming soon!<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-86c02cc e-flex e-con-boxed e-con e-parent\" data-id=\"86c02cc\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-479ead2 e-con-full e-flex e-con e-child\" data-id=\"479ead2\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5a111e0 elementor-arrows-position-inside elementor-pagination-position-outside elementor-widget elementor-widget-image-carousel\" data-id=\"5a111e0\" data-element_type=\"widget\" data-settings=\"{&quot;slides_to_show&quot;:&quot;1&quot;,&quot;effect&quot;:&quot;fade&quot;,&quot;navigation&quot;:&quot;both&quot;,&quot;autoplay&quot;:&quot;yes&quot;,&quot;pause_on_hover&quot;:&quot;yes&quot;,&quot;pause_on_interaction&quot;:&quot;yes&quot;,&quot;autoplay_speed&quot;:5000,&quot;infinite&quot;:&quot;yes&quot;,&quot;speed&quot;:500}\" data-widget_type=\"image-carousel.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-carousel-wrapper swiper\" role=\"region\" aria-roledescription=\"carousel\" aria-label=\"\u753b\u50cf\u30ab\u30eb\u30fc\u30bb\u30eb\" dir=\"ltr\">\n\t\t\t<div class=\"elementor-image-carousel swiper-wrapper\" aria-live=\"off\">\n\t\t\t\t\t\t\t\t<div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"1 of 2\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/iStock-512051390.jpg\" alt=\"antibodies to cell movement of the virus\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"2 of 2\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/iStock-2197456331.jpg\" alt=\"Vials of a fictitious mRNA based cancer treatment. Large group of vials with one standing in front, selective focus on foreground\" \/><\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-prev\" role=\"button\" tabindex=\"0\">\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-chevron-left\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M646 125C629 125 613 133 604 142L308 442C296 454 292 471 292 487 292 504 296 521 308 533L604 854C617 867 629 875 646 875 663 875 679 871 692 858 704 846 713 829 713 812 713 796 708 779 692 767L438 487 692 225C700 217 708 204 708 187 708 171 704 154 692 142 675 129 663 125 646 125Z\"><\/path><\/svg>\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-next\" role=\"button\" tabindex=\"0\">\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-chevron-right\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M696 533C708 521 713 504 713 487 713 471 708 454 696 446L400 146C388 133 375 125 354 125 338 125 325 129 313 142 300 154 292 171 292 187 292 204 296 221 308 233L563 492 304 771C292 783 288 800 288 817 288 833 296 850 308 863 321 871 338 875 354 875 371 875 388 867 400 854L696 533Z\"><\/path><\/svg>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"swiper-pagination\"><\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9ff7022 e-con-full e-flex e-con e-child\" data-id=\"9ff7022\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-28ee30f e-con-full e-flex e-con e-child\" data-id=\"28ee30f\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e0da48a elementor-widget elementor-widget-heading\" data-id=\"e0da48a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Advancing Diagnostics and Therapeutics<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-797fbd6 e-con-full e-flex e-con e-child\" data-id=\"797fbd6\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8e4a0e2 elementor-widget elementor-widget-text-editor\" data-id=\"8e4a0e2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"79\" data-end=\"379\">In 2019, cancer genomic medicine entered a new era in Japan. By analyzing the genetic alterations in tumor tissues, it has become possible to select the most suitable molecular-targeted therapies based on individual genomic profiles\u2014bringing us one step closer to truly personalized cancer treatment.<\/p><p data-start=\"381\" data-end=\"626\">However, in the case of oral cancer, the number of approved molecular-targeted drugs remains limited. Consequently, there are still relatively few patients for whom cancer genomic medicine leads directly to the selection of effective treatments.<\/p><p data-start=\"628\" data-end=\"804\">To address this gap, we are working to develop novel diagnostic tools and therapeutic strategies based on the mechanisms of genetic alterations and aberrant signaling pathways.<\/p><p data-start=\"806\" data-end=\"1011\">Our research explores a wide range of therapeutic modalities, including antibodies, small molecules, peptides, and mRNA-based agents, with the goal of realizing the future of precision medicine for cancer.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8f7a8cc e-flex e-con-boxed e-con e-parent\" data-id=\"8f7a8cc\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-fea33cd e-con-full e-flex e-con e-child\" data-id=\"fea33cd\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-9b74268 e-con-full e-flex e-con e-child\" data-id=\"9b74268\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9f72b62 elementor-widget elementor-widget-heading\" data-id=\"9f72b62\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Precise and Advanced Oral Pathology Diagnostics by Certified Specialists\nFostering the Next Generation of Globally Active Oral Pathologists<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fcc0ab9 e-con-full e-flex e-con e-child\" data-id=\"fcc0ab9\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-453f3a4 elementor-widget elementor-widget-text-editor\" data-id=\"453f3a4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"72\" data-end=\"459\">In oral pathology, the diagnosis of various diseases occurring in the oral and maxillofacial region\u2014particularly oral squamous cell carcinoma, odontogenic tumors, and salivary gland tumors\u2014requires a high level of expertise, clinical experience, and diagnostic skill. As such, obtaining board certification as a specialist in oral pathology or oral cytopathology is strongly recommended.<\/p><p data-start=\"461\" data-end=\"943\">With the recent advances in cancer genomic medicine, oral pathologists are increasingly expected to contribute to companion diagnostics for predicting the efficacy of molecular-targeted therapies, as well as to participate in expert panels. In this context, qualification as a certified specialist in molecular pathology (oral) is also becoming essential. Our laboratory provides a structured training system to support graduate students in obtaining these professional credentials.<\/p><p data-start=\"945\" data-end=\"1367\">While oral pathology has traditionally developed through morphology-based approaches, the field is now evolving into \u201cnext-generation digital oral pathology,\u201d incorporating genetic and proteomic analysis along with cutting-edge technologies such as artificial intelligence. In our lab, we integrate these multimodal technologies to help students acquire practical skills applicable to research, education, and diagnostics.<\/p><p data-start=\"1369\" data-end=\"1651\">Furthermore, through daily use of English, opportunities for studying abroad, and participation in international conferences, we actively support the development of globally engaged oral pathology specialists who can contribute to the international medical and scientific community.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b318c2a e-con-full e-flex e-con e-child\" data-id=\"b318c2a\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7a4c235 elementor-widget__width-initial elementor-arrows-position-inside elementor-pagination-position-outside elementor-widget elementor-widget-image-carousel\" data-id=\"7a4c235\" data-element_type=\"widget\" data-settings=\"{&quot;slides_to_show&quot;:&quot;1&quot;,&quot;effect&quot;:&quot;fade&quot;,&quot;navigation&quot;:&quot;both&quot;,&quot;autoplay&quot;:&quot;yes&quot;,&quot;pause_on_hover&quot;:&quot;yes&quot;,&quot;pause_on_interaction&quot;:&quot;yes&quot;,&quot;autoplay_speed&quot;:5000,&quot;infinite&quot;:&quot;yes&quot;,&quot;speed&quot;:500}\" data-widget_type=\"image-carousel.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-carousel-wrapper swiper\" role=\"region\" aria-roledescription=\"carousel\" aria-label=\"\u753b\u50cf\u30ab\u30eb\u30fc\u30bb\u30eb\" dir=\"ltr\">\n\t\t\t<div class=\"elementor-image-carousel swiper-wrapper swiper-image-stretch\" aria-live=\"off\">\n\t\t\t\t\t\t\t\t<div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"1 of 3\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/652188ec2855cb2314f95015.jpg\" alt=\"652188ec2855cb2314f95015\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"2 of 3\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/iStock-942229406.jpg\" alt=\"PCR DNA sequence analysis by chromatogram peaks\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"3 of 3\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/iStock-1286469130-2.jpg\" alt=\"Global image centered on Asia for business and logistics etc.\" \/><\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-prev\" role=\"button\" tabindex=\"0\">\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-chevron-left\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M646 125C629 125 613 133 604 142L308 442C296 454 292 471 292 487 292 504 296 521 308 533L604 854C617 867 629 875 646 875 663 875 679 871 692 858 704 846 713 829 713 812 713 796 708 779 692 767L438 487 692 225C700 217 708 204 708 187 708 171 704 154 692 142 675 129 663 125 646 125Z\"><\/path><\/svg>\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-next\" role=\"button\" tabindex=\"0\">\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-chevron-right\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M696 533C708 521 713 504 713 487 713 471 708 454 696 446L400 146C388 133 375 125 354 125 338 125 325 129 313 142 300 154 292 171 292 187 292 204 296 221 308 233L563 492 304 771C292 783 288 800 288 817 288 833 296 850 308 863 321 871 338 875 354 875 371 875 388 867 400 854L696 533Z\"><\/path><\/svg>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"swiper-pagination\"><\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b911bd2 e-flex e-con-boxed e-con e-parent\" data-id=\"b911bd2\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e86ca32 elementor-widget elementor-widget-spacer\" data-id=\"e86ca32\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-16c08d5 e-flex e-con-boxed e-con e-parent\" data-id=\"16c08d5\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3171fb1 elementor-widget elementor-widget-heading\" data-id=\"3171fb1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">News!!<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3b15ba3 e-flex e-con-boxed e-con e-parent\" data-id=\"3b15ba3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ae91e34 elementor-widget elementor-widget-text-editor\" data-id=\"ae91e34\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Professor Toshinori Ando assumed the position in the Department of Oral and Maxillofacial Pathobiology on August 1, 2025.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ec33041 e-flex e-con-boxed e-con e-parent\" data-id=\"ec33041\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c28a5e2 elementor-widget elementor-widget-spacer\" data-id=\"c28a5e2\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d2b33e5 e-flex e-con-boxed e-con e-parent\" data-id=\"d2b33e5\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5456801 elementor-widget elementor-widget-heading\" data-id=\"5456801\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SNS\uff08facebook, instagram, X\uff09<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b1186ee elementor-shape-rounded elementor-grid-0 e-grid-align-center elementor-widget elementor-widget-social-icons\" data-id=\"b1186ee\" data-element_type=\"widget\" data-widget_type=\"social-icons.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-social-icons-wrapper elementor-grid\" role=\"list\">\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-facebook elementor-repeater-item-aa585f9\" href=\"https:\/\/www.facebook.com\/profile.php?id=61577895309020\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Facebook<\/span>\n\t\t\t\t\t\t<svg class=\"e-font-icon-svg e-fab-facebook\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.78 90.69 226.38 209.25 245V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.31 482.38 504 379.78 504 256z\"><\/path><\/svg>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-x-twitter-square elementor-repeater-item-d564834\" href=\"https:\/\/x.com\/oralpath_hu\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">X-twitter-square<\/span>\n\t\t\t\t\t\t<svg class=\"e-font-icon-svg e-fab-x-twitter-square\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M64 32C28.7 32 0 60.7 0 96V416c0 35.3 28.7 64 64 64H384c35.3 0 64-28.7 64-64V96c0-35.3-28.7-64-64-64H64zm297.1 84L257.3 234.6 379.4 396H283.8L209 298.1 123.3 396H75.8l111-126.9L69.7 116h98l67.7 89.5L313.6 116h47.5zM323.3 367.6L153.4 142.9H125.1L296.9 367.6h26.3z\"><\/path><\/svg>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-instagram elementor-repeater-item-58934da\" href=\"https:\/\/www.instagram.com\/oralpathologyhiroshima\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Instagram<\/span>\n\t\t\t\t\t\t<svg class=\"e-font-icon-svg e-fab-instagram\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224.1 141c-63.6 0-114.9 51.3-114.9 114.9s51.3 114.9 114.9 114.9S339 319.5 339 255.9 287.7 141 224.1 141zm0 189.6c-41.1 0-74.7-33.5-74.7-74.7s33.5-74.7 74.7-74.7 74.7 33.5 74.7 74.7-33.6 74.7-74.7 74.7zm146.4-194.3c0 14.9-12 26.8-26.8 26.8-14.9 0-26.8-12-26.8-26.8s12-26.8 26.8-26.8 26.8 12 26.8 26.8zm76.1 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elementor-widget elementor-widget-spacer\" data-id=\"3915326\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7958401 e-flex e-con-boxed e-con e-parent\" data-id=\"7958401\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a2627a2 elementor-widget elementor-widget-heading\" data-id=\"a2627a2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Address<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f42ac3b e-flex e-con-boxed e-con e-parent\" data-id=\"f42ac3b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-6279e6c e-con-full e-flex e-con e-child\" data-id=\"6279e6c\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b7788e6 elementor-widget elementor-widget-text-editor\" data-id=\"b7788e6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>5th Floor, Basic and Social Medicine Building<\/p><p>1-2-3 Kasumi, Minami-ku, Hiroshima 7348553<\/p><p>Department of Oral and Maxillofacial\u00a0 Pathobiology, Graduate School of Biomedical and Health Sciences, Hiroshima University<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cdb69cb elementor-widget elementor-widget-google_maps\" data-id=\"cdb69cb\" data-element_type=\"widget\" data-widget_type=\"google_maps.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-custom-embed\">\n\t\t\t<iframe loading=\"lazy\"\n\t\t\t\t\tsrc=\"https:\/\/maps.google.com\/maps?q=%E5%BA%83%E5%B3%B6%E5%A4%A7%E5%AD%A6%E7%97%85%E9%99%A2&#038;t=m&#038;z=10&#038;output=embed&#038;iwloc=near\"\n\t\t\t\t\ttitle=\"\u5e83\u5cf6\u5927\u5b66\u75c5\u9662\"\n\t\t\t\t\taria-label=\"\u5e83\u5cf6\u5927\u5b66\u75c5\u9662\"\n\t\t\t><\/iframe>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e4994cd e-flex e-con-boxed e-con e-parent\" data-id=\"e4994cd\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a384ee7 elementor-widget elementor-widget-spacer\" data-id=\"a384ee7\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e41cc21 e-flex e-con-boxed e-con e-parent\" data-id=\"e41cc21\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d95652b elementor-widget elementor-widget-image\" data-id=\"d95652b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"768\" src=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/F3ED0B71-221B-499F-8698-4C6906446013-1024x768.jpeg\" class=\"attachment-large size-large wp-image-975\" alt=\"\" srcset=\"https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/F3ED0B71-221B-499F-8698-4C6906446013-1024x768.jpeg 1024w, https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/F3ED0B71-221B-499F-8698-4C6906446013-300x225.jpeg 300w, https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/F3ED0B71-221B-499F-8698-4C6906446013-768x576.jpeg 768w, https:\/\/oralpathology.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/07\/F3ED0B71-221B-499F-8698-4C6906446013.jpeg 1477w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7fa90c5 e-flex e-con-boxed e-con e-parent\" data-id=\"7fa90c5\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-708c63c elementor-widget elementor-widget-text-editor\" data-id=\"708c63c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The new Oral Pathology team at Hiroshima University has officially launched as of August 1, 2025.<br data-start=\"97\" data-end=\"100\" \/>We appreciate your continued support and look forward to this new beginning!<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Department of Oral and Maxillofacial Pathobiology, Hiroshima University Japanese Page Greetings from the Profe 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